Evolving Role of Bone Biomarkers in Castration-Resistant Prostate Cancer

Evolving role of chemotherapy in castration-resistant prostate cancer

The role of chemotherapy in castration-resistant prostate cancer has evolved greatly over the past several decades. However, at this time, docetaxel remains the only first-line chemotherapy option that improves survival. More recently, the novel taxane cabazitaxel (plus prednisone) was found to prolong overall survival in metastatic castration-resistant patients who had progressed during or aft...

Single Orbital Metastasis in Castration-Resistant Prostate Cancer

Introduction: Orbital metastasis of prostate cancer (PC) is very rare and even more unique in castration-resistant PC (CRPC). In this scenario, choline positron emission tomography/computed tomography (choline PET/CT) is the gold-standard restaging method of choice available in our setting, and new anti-androgens treatments show improvement in overall survival. Case presentation: We report the...

Single Orbital Metastasis in Castration-Resistant Prostate Cancer

Introduction: Orbital metastasis of prostate cancer (PC) is very rare and even more unique in castration-resistant PC (CRPC). In this scenario, choline positron emission tomography/computed tomography (choline PET/CT) is the gold-standard restaging method of choice available in our setting, and new anti-androgens treatments show improvement in overall survival. Case presentation: We report the...

Prognostic and predictive biomarkers in metastatic castration-resistant prostate cancer.

AJA Biomarkers are any manifestation of a biological process, particularly in patients, that can be measured quantitatively. They can reflect either normal (physiologic) or disease (pathophysiologic) processes. Biomarkers are used in various contexts in prostate cancer. Prognostic biomarkers are related to the natural history of a disease over time, whereas predictive biomarkers are linked to t...

Exosomal microRNAs as potential biomarkers in castration-resistant prostate cancer.